Representation of Parts within the Foundational Model of Anatomy Ontology
نویسنده
چکیده
As biomedical ontologies grow in size and complexity it is crucial to develop methods for detecting inconsistencies within ontologies. The Foundational Model of Anatomy (FMA) ontology represents knowledge of human anatomy, with structural organization provided by class and part relationships. Using a manual audit, I identify types of inconsistencies arising from class and regional part relationships for regions of the body and the parts of organs. Inconsistencies arise from both explicitly declared relationships and relationships that are implied by the lexical constructs of class names. The purpose of this work is to propose methods of structural organization and lexical consistency that will make the FMA more compatible with computational auditing and increase its usability. Keywords—ontology; partonomy; anatomy
منابع مشابه
Proposed Classification of Cells in the Foundational Model of Anatomy
A logical and principled representation of cell types and their component parts could serve as a framework for correlating the various ontologies that are emerging in bioinformatics with a focus on cells and subcellular biological entities. In order to address this need we have extended the Foundational Model of Anatomy (FMA)1,2 from macroscopic to cellular and subcellular anatomical entities. ...
متن کاملRepresenting Complexity in Part-Whole Relationships within the Foundational Model of Anatomy
The Foundational Model of Anatomy (FMA) is a frame-based ontology that represents declarative knowledge about the structural organization of the human body. Part-whole relationships play a particularly important role in this representation. In order to assure that knowledge-based applications relying on the FMA as a resource can reason about anatomy, we have modified and enhanced currently avai...
متن کاملComparing the Representation of Anatomy in the FMA and SNOMED CT
OBJECTIVE This paper reports on the alignment between two large ontologies of anatomy: the Foundational Model of Anatomy (FMA) and the representation of anatomical structures in SNOMED CT. The objective of this study is to investigate the compatibility between a reference ontology of anatomy (the FMA, 75,019 concepts) and a representation of anatomy created for use in clinical applications (SNO...
متن کاملModel Formulation: Modeling Functional Neuroanatomy for an Anatomy Information System
OBJECTIVE Existing neuroanatomical ontologies, databases and information systems, such as the Foundational Model of Anatomy (FMA), represent outgoing connections from brain structures, but cannot represent the "internal wiring" of structures and as such, cannot distinguish between different independent connections from the same structure. Thus, a fundamental aspect of Neuroanatomy, the function...
متن کاملMulti-species Ontologies of the Craniofacial Musculoskeletal System
We created the Ontology of Craniofacial Development and Malformation (OCDM) [1] to provide a unifying framework for organizing and integrating craniofacial data ranging from genes to clinical phenotypes from multi-species. Within this framework we focused on spatio-structural representation of anatomical entities related to craniofacial development and malformation, such as craniosynostosis and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2016